Journal of Korean Geriatric Psychiatry

노인정신의학

pISSN 1226-6329 / eISSN 2733-4600


노인정신의학

대한노인정신의학회 (17권2호 47-55)

Treatment of Late-Life Depression by Brain Stimulation Techniques

뇌 자극술을 이용한 노년기 우울증의 치료

정동청(Dong Chung Jung);강웅구(Ung Gu Kang);김용식(Yong Sik Kim)

Abstract

Due to the low response rate of antidepressant treatment in late-life depression, brain stimulation techniques should be considered when treating elderly patients. Electroconvulsive therapy (ECT) is one of the most frequently used brain stimulation techniques, and shows favorable outcome and acceptable tolerability in the treatment of late-life depression. Hemodynamic change and cognitive impairment are common side effects of ECT, which are transient in most cases. Since cognitive impairment can lead to treatment non-compliance, it should be minimized by controlling electrode position, pulse-width, treatment frequency, etc. Because ECT is followed by rapid cardiovascular change, risk factors should be evaluated and managed properly. Transcranial magnetic stimulation (TMS) and magnetic seizure therapy (MST) are also shown to be effective in treating depression, with less cognitive impairment. However, further research is needed to establish their efficacy in late-life depression.

Keywords

노인,우울증,뇌 자극술,전기경련치료,경두개자기자극술,자기경련치료 Aged,Depression,Brain stimulation techniques,Eelectroconvulsive therapy (ECT),Transcranial magnetic stimulation (TMS),Magnetic seizure therapy (MST)