Journal of Korean Geriatric Psychiatry

노인정신의학

pISSN 1226-6329 / eISSN 2733-4600


노인정신의학

대한노인정신의학회 (11권1호 40-43)

Prescription Pattern of Risperidone and Olanzapine for Elderly Psychiatric Inpatients in a Naturalistic Setting

노인 입원 환자에 대한 일 대학 병원의 리스페리돈과 올란자핀의 처방 경향

임현국(Hyun Kook Lim);최은형(Eun Hyung Choi);이영란(Young Ran Lee);오근(Keun Oh);배치운(Chi Un Pae);이철(Chul Lee);백인호(In Ho Paik);이창욱(Chang Uk Lee)

Abstract

Several studies have reported that either risperidone or olanzapine is effective and tolerable in the elderly patients with psychotic symptoms. However, there is a lack of clinical data of risperidone and olanzapine prescription for elderly patients in the Aisan population. We reviewed retrospectively the medical records of risperidone (n=112) and olanzapine (n=96) treated patients older than age 60 who were admitted to a university-affiliated hospital between October 2005 and August 2006. The mean daily dose of risperidone was 3.4±1.5 mg and olanzapine, 8.8±5.6 mg, respectively. The response rate on the CGI (much and very much improved) appeared to be 67.4% in the risperidone group and 70.8% in the olanzapine group, respectively. Adverse events were reported in 48.2% in the risperidone group and 46.9% in the olanzapine group, without serious adverse events, respectively. This study showed that either risperidone or olanzapine would be effective and tolerable in elderly patients with psychotic symptoms and that provides similar results to those reported from western countries.

Keywords

리스페리돈,올란자핀,노인,정신병, Olanzapine,Risperidone,Old age,Psychosis