Journal of Korean Geriatric Psychiatry

노인정신의학

pISSN 1226-6329 / eISSN 2733-4600


노인정신의학

대한노인정신의학회 (5권1호 50-57)

Reliability and Analysis of Symptom Category Scores of the Behavior Pathology in Alzheimer’s Disease Rating Scale, Korean Version(BEHAVE-AD-K)

알쯔하이머병의 행동적 정신병리 평가척도 한국어판 (BEHAVE-AD-K)의 신뢰도 및 증상군별 점수 분석

서국희(Guk-Hee Suh);손현균(Hyun Gyun Son);신형주(Hyongju Shin);김인명(In-Myoung Kim);홍상의(Sangeui Hong);박종한(Jonghan Park);최인근(Ihn-Geun Choi);김상국(Sang Kook Kim);연병길(Byeong Kil Yeon)

Abstract

Objective:The aims of this study were to (1) validate the inter-rater reliability of the BEHAVE-AD, Korean version, to (2) analyze the quantitative relationship between severity of Alzheimer's disease (AD) and mean scores on each of the BEHAVE-AD categories and mean total BEHAVE-AD score. Design:Cross-sectional study of geriatric patients with AD evaluated at a mental hospital for the elderly. Sample:Fifty-two consecutive patients diagnosed with probable Alzheimer's disease (AD) according to NINCDS-ADRDA diagnostic criteria. Results:In reliability study, significant correlations were obtained for all BEHAVE-AD symptoms category scores and for mean total BEHAVE-AD scores. Analysis of BEHAVE-AD scores as a function of disease severity demonstrated a non-linear relationship between severity of behavioral symptoms and the global and cognitive advance of AD. Score analysis of the BEHAVE-AD indicates that these behavioral disturbances become most severe in the moderate and moderately severe stages of AD. Conclusion:All the results proved the cross-cultural validity and reliability of the BEHAVEAD, Korean version. Furthermore, these results have implications for the methodology of pharmacological trials of putative cognitive enhancer compounds in AD.

Keywords

알쯔하이머병,치매,행동 장애,정신증,행동적 정신병리, Alzheimer's disease,Dementia,Behavioral disturbances,Psychosis,Behavioral pathology